Corrigendum: Oxygen, Gastrin-Releasing Peptide, and Pediatric Lung Disease: Life in the Balance
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منابع مشابه
Corrigendum: Oxygen, Gastrin-Releasing Peptide, and Pediatric Lung Disease: Life in the Balance
Excessive oxygen (O2) can cause tissue injury, scarring, aging, and even death. Our laboratory is studying O2-sensing pulmonary neuroendocrine cells (PNECs) and the PNEC-derived product gastrin-releasing peptide (GRP). Reactive oxygen species (ROS) generated from exposure to hyperoxia, ozone, or ionizing radiation (RT) can induce PNEC degranulation and GRP secretion. PNEC degranulation is also ...
متن کاملgastrin releasing peptide and pentagastrin
Accepted for publication 9 November 1995 Abstract Background-Patients with duodenal ulcer (DU) have high basal (BAO) and peak (PAO) acid outputs. The effect of Helicobacter pylori eradication on these variables is unclear. Aim-To discover if gastric acid hypersecretion in patients with DU is caused by Hpylori. Patients and methods-BAO, gastrin releasing peptide (GRP), and pentagastrin stimulate...
متن کاملGastrin releasing peptide and gastrin releasing peptide receptor expression in gastrointestinal carcinoid tumours.
AIMS To establish whether gastrin releasing peptide (GRP) and the GRP receptor (GRPR) are expressed together in gastrointestinal carcinoid tumours. METHODS Twenty six carcinoid tumours from the stomach, small intestine, appendix, and colorectum were investigated by immunohistochemistry for GRP and GRPR. RESULTS GRP was detected in nine of 19 tumours and GRPR in 22 of 26. Coexpression of bot...
متن کاملMolecular basis of the selectivity of gastrin-releasing peptide receptor for gastrin-releasing peptide.
The mammalian bombesin peptides [gastrin-releasing peptide (GRP) and neuromedin B (NMB)] are important in numerous biological and pathological processes. These effects are mediated by the heptahelical GRP receptor (GRPR) and NMB receptor (NMBR). GRP has high affinity for GRPR and lower affinity for NMBR. Almost nothing is known about the molecular basis for the selectivity of GRP. To address th...
متن کاملCombined measurements of neuron specific enolase and bombesin/gastrin releasing peptide in lung cancer.
Pretreatment serum neuron specific enolase (NSE) and plasma bombesin/gastrin releasing peptide (BN/GRP) were measured in 92 lung cancer patients and 17 controls. The mean level of NSE (p less than 0.001) and BN/GRP (p less than 0.05) was significantly raised in patients with small cell lung cancer (SCLC, n = 62) compared to non-SCLC (n = 30) and controls. The mean concentration of NSE in extens...
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ژورنال
عنوان ژورنال: Frontiers in Pediatrics
سال: 2014
ISSN: 2296-2360
DOI: 10.3389/fped.2014.00102